Q. How is the FIT test different from other fecal occult blood tests (FOBT)?
A. Both Fecal Immunochemical Testing (FIT) and Fecal Occult Blood Tests (FOBT) are tests used to detect the presence of blood in the stool, as an indication of colorectal cancer. The difference between the two tests is:
  • FOBT uses a chemical indicator that shows a color change in the presence of blood, whereas FIT uses antibodies directed against human hemoglobin to detect blood in the stool. FIT is considered a more accurate way to screen for blood in the stools as it only detects human blood from the lower intestines.
  • FOBT requires dietary and medication restrictions but FIT does not require any dietary or medication restrictions.
  • Multiple stool collections are required for FOBT results, but for FIT, only a single collection is required.
Fecal Immunochemical Testing (FIT)
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